Acetoacetate and Acetate, Intermediates in Glutarate Catabolism

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Acetoacetate and acetate, intermediates in glutarate catabolism.

The labeling patterns found in tissue glutamate, aspartate, and alanine after administration of glutaric acid-3-Cl4 to male rats (1) indicated that the major catabolic route of glutarate is via acetate (2) and not via a direct conversion to the carbon chain of cu-ketoglutarate (3-5). In further studies on the metabolism of glutarate-3-C14 in rats, we have observed the formation of urinary acety...

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Enzymatic condensation of acetate to acetoacetate in liver extracts.

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Acetoacetate Formation in Liver

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1961

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)64369-8